All

All
Insight
Research Services
Preclinical CRO
Animal Resource Bank

Animal welfare

Respect for Life ● Scientific Management ● Empowering Innovation

Based on a commitment to the welfare of laboratory animals, we have established a scientific, humane, and sustainable management system for experimental animals. Aniphe BioLab strictly adheres to ethical guidelines. Upholding the 3R principles, we have implemented an animal welfare management system that covers the entire life cycle, ensuring animal health and well-being while supporting high‑quality research and innovation.

Ethical Compliance

Review and Supervision

Scientific Management

Full Lifecycle Management

Highly Reliable in Quality

Ensure stable and reliable quality.

Standard Certification

Follow authoritative regulatory guidelines.

Animal Welfare Management System

The Animal Care and Use Committee provides oversight throughout the entire process, ensuring both animal welfare and experimental quality.

Experimental Protocol Review

Ethical review: necessity of the experiment, rationality of the study design, number of animals, and endpoints, among other considerations.

Regular facility inspections

Conduct routine inspections of animal housing and experimental facilities, verifying the implementation of welfare measures such as environmental enrichment, stocking density, and operational protocols.

Personnel Training Management

Regularly conduct specialized training on animal welfare, ethics, and standardized operating procedures.

Comprehensive project review

Ongoing reviews are conducted for animal‑related projects, including breeding, model generation, pharmacology, and euthanasia, to ensure that welfare measures are fully implemented throughout the entire process.

Real-time violation control

Upon identifying any practices that harm animals or violate animal welfare standards, the authority shall have the right to immediately suspend the relevant experimental activities and may resume them only after corrective measures have been implemented and verified.

Five Commitments to Animal Welfare

The Animal Care and Use Committee provides oversight throughout the entire process, ensuring both animal welfare and experimental quality.

Adhere to the 3R core principles

The 3R principles—replace, reduce, and refine—are applied throughout the entire process, with animal use minimized to the greatest extent possible while meeting scientific research needs, and pain and stress in animals are eliminated through technological improvements.

High-standard rearing environment

SPF‑plus facilities provide a stable, temperature‑ and humidity‑controlled environment, ample clean drinking water, and customized, precision feeding, complemented by environmental enrichment amenities to ensure animals’ comfortable living conditions.

Scientific research and innovation do not compromise animal welfare.

During the project initiation phase, the necessity of animal use is assessed concurrently, and experiments that compromise animal welfare are rejected, thereby striking a balance between scientific rigor and bioethical considerations.

Refined Management System

End-to-end operational logs are traceable, meeting the audit requirements of laboratories and pharmaceutical companies across various regions.

Upholding Industry Responsibility

Promote the industry’s advancement in laboratory animals.
Transmission of Benefit Awareness

Adhere to the 3R principles

Reduction

Reduce the number of laboratory animals used while ensuring the scientific rigor and validity of experimental data.

A well‑designed sample size helps avoid unnecessary repeated experiments.
Optimize the experimental design to make full use of existing data and resources.
Employ statistical methods to enhance the information-gathering efficiency of a single experiment.

Replacement

Prioritize the use of non-animal models, lower-order organisms, or in vitro methods to replace experiments involving higher-order animals.

In vitro cell/organoid models, organ-on-a-chip
Computer simulations, mathematical models, AI predictions
Low‑order model organisms are used to replace rodents and primates in conducting preliminary screening assays.

Optimization Refinement

To the greatest extent possible, alleviate or eliminate animal pain, suffering, and stress responses.

Optimize surgical procedures and employ minimally invasive techniques.
Rational use of anesthesia and analgesia protocols
Improving the rearing environment (enriching cage furnishings, group housing, and environmental enrichment)
Establish a humane endpoint to prevent animals from experiencing unnecessary suffering.

Comply with laws and ethical standards

Aniphe BioLab conducts its laboratory animal management in strict compliance with relevant national and industry regulations and guidelines, continuously refining its animal welfare policies, operational procedures, and quality management system to ensure that the entire process of using laboratory animals meets ethical requirements and scientific research standards.

“GBT 35892-2018 Guidelines for Ethical Review of Laboratory Animal Welfare”

“Guide to the Care and Use of Laboratory Animals, Eighth Edition”

“Guiding Opinions on the Humane Treatment of Laboratory Animals, 2006”

Measures for the Administration of Laboratory Animals of Jiangsu Province