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Animal models of other diseases

Aniphe BioLab develops a range of additional disease models, including allergic conjunctivitis (AC), iron deficiency anemia (IDA), aging-related models, systemic lupus erythematosus (SLE), and experimental autoimmune myositis (EAM). These models cover diverse pathological processes, such as immune dysregulation, impaired hematopoiesis, and age-related degeneration, supporting disease mechanism studies and drug efficacy evaluation.
Building on its established model portfolio, Aniphe BioLab continues to expand and optimize modeling approaches in response to emerging research needs and translational medicine. We offer flexible model development, from established disease models to novel mechanism-based models, with customized strategies tailored to specific research objectives.

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Mechanism-oriented
Precision Modeling

Multiple reviews
System Verification

Phenotypic stability
Repeatability

University Support
Accelerate R&D

Related Resources

Psychiatric & neurological disease models

Cardiovascular disease model

Respiratory disease model

Endocrine and Immune system models

Digestive system models

Urinary system disease model

Bone-related disease model

Oral disease models

Reproductive system disease model

Skin-related disease models

Animal models of other diseases

Product List:

Disease Name	Disease model	Details
Glioblastoma	U87-MG-luc orthotopic animal model	View details →
Alzheimer's disease	Alzheimer’s disease AD animal model	View details →
Encephalomyelitis	Allergic encephalomyelitis animal model of AE	View details →
Post-traumatic stress disorder	Animal model of post-traumatic stress disorder (PTSD)	View details →
Traumatic brain injury	Animal model of traumatic brain injury	View details →
Epilepsy	Epilepsy animal model	View details →
Spinal cord injury	Animal model of spinal cord injury	View details →
Anxiety disorder	Anxiety disorder animal model	View details →
Neurological dysfunction after TBI	Animal model of electrical stimulation for traumatic brain injury	View details →
Traumatic brain injury	Animal model of traumatic brain injury	View details →
Depression	Chronic Unpredictable Mild Stress (CUMS) animal model	View details →
Hemorrhagic stroke	Animal model of cerebral hemorrhage	View details →
	Cerebral ischemia MCAO animal model	View details →
Sepsis-associated encephalopathy	Sepsis-induced brain injury model	View details →
Parkinson's disease	Parkinson’s disease (PD) animal model	View details →
Hepatic encephalopathy (early stage)	Mild hepatic encephalopathy model	View details →
Hypoxic-ischemic brain injury	Hypoxic-ischemic encephalopathy (HIE) animal model	View details →
Trigeminal neuralgia	Trigeminal neuralgia animal model	View details →
Sleep disorder	Animal models of sleep disorders/insomnia	View details →
Vascular dementia	Vascular dementia animal model	View details →
Depression	Animal model of depression	View details →
Multiple sclerosis	Animal model of autoimmune encephalomyelitis	View details →
Neuropathic pain	Sciatic nerve compression animal model	View details →

Disease Name	Disease model	Construction method
Migraine	Migraine model	Nitroglycerin injection, dural inflammation-induced stimulation (application of inflammatory substances)
Hypopituitarism	Pituitaryectomy model	Surgical removal of the pituitary gland (via the transsphenoidal or transcranial approach)
Suppurative osteomyelitis	Experimental model of osteomyelitis	Tibial drilling and injection of Staphylococcus aureus
Ischemic tolerance induction	Hypoxic preconditioning model	Severe ischemia induced after repeated brief hypoxic exposures (in normobaric or hypobaric chambers)
Vestibular dysfunction	Unilateral labyrinthectomy model	Surgical destruction of the unilateral vestibular organ in rats and guinea pigs.
Antipsychotic-induced bone loss	Schizophrenia-induced osteoporosis model	Long-term administration of antipsychotic agents (such as haloperidol) in combination with ovariectomy or glucocorticoid induction
Periprosthetic osteolysis	Cranial bone dissolution model	Cranial implantation of titanium particles or inflammatory factors (TNF-α/polyethylene particles)
Post-ischemic epilepsy	Global cerebral ischemic epilepsy model	Seizures following bilateral common carotid artery ligation combined with hypotension-induced ischemia