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Urinary system disease model
Aniphe BioLab develops urinary system disease models based on key pathological mechanisms, including impaired renal filtration, urinary tract inflammation, and metabolic injury. These models support in vivo research on nephritis, renal fibrosis, urinary tract infections, and metabolic kidney injury.
By reproducing renal inflammation, glomerular injury, and changes in the urinary tract microenvironment, our models provide reliable platforms for disease mechanism studies and drug evaluation. Applications include renoprotective, anti-inflammatory, and antifibrotic therapies, as well as research on renal dysfunction and urinary tract infections.
Precision Modeling
System Verification
Repeatability
Accelerate R&D
Related Resources
Characteristics of the Aniphe BioLab Urinary System Disease Model
In response to the research needs surrounding renal injury and urinary system dysfunction, Aniphe BioLab has established a standardized animal model system for urological diseases, ensuring model stability and experimental reproducibility.
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It encompasses common disease models, including nephritis, renal fibrosis, acute and chronic kidney injury, and urinary tract infections, thereby meeting multi-level research needs. |
Standardize the modeling method, induction dose, and time window to minimize the impact of individual variability on experimental outcomes. |
By integrating renal function parameters, histopathological findings, and inflammatory cytokine assays, a comprehensive assessment of structural damage and functional alterations can be achieved. |
Provide raw experimental data, pathological images, and analytical results to ensure data traceability and compliance with publication and regulatory submission requirements. |
Animal models of urological diseases, by mimicking renal injury and functional abnormalities, provide a stable and reproducible in vivo experimental platform for studying disease mechanisms and developing therapeutic agents.
Product List:
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Disease Name |
Disease model |
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U87-MG-luc orthotopic animal model |
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Alzheimer’s disease AD animal model |
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Allergic encephalomyelitis animal model of AE |
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Animal model of post-traumatic stress disorder (PTSD) |
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Animal model of traumatic brain injury |
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Epilepsy animal model |
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Animal model of spinal cord injury |
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Anxiety disorder animal model |
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Animal model of electrical stimulation for traumatic brain injury |
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Animal model of traumatic brain injury |
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Chronic Unpredictable Mild Stress (CUMS) animal model |
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Animal model of cerebral hemorrhage |
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Cerebral ischemia MCAO animal model |
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Sepsis-induced brain injury model |
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Parkinson’s disease animal model |
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Mild hepatic encephalopathy model |
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Hypoxic-ischemic encephalopathy (HIE) animal model |
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Trigeminal neuralgia animal model |
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Animal models of sleep disorders/insomnia |
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Vascular dementia animal model |
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Animal model of depression |
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Animal model of autoimmune encephalomyelitis |
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Sciatic nerve compression animal model |
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Disease Name |
Disease model |
Construction method |
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Migraine model |
Nitroglycerin injection, dural inflammation-induced stimulation (application of inflammatory substances) |
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Pituitaryectomy model |
Surgical removal of the pituitary gland (via the transsphenoidal or transcranial approach) |
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Experimental model of osteomyelitis |
Tibial drilling and injection of Staphylococcus aureus |
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Hypoxic preconditioning model |
Severe ischemia induced after repeated brief hypoxic exposures (in normobaric or hypobaric chambers) |
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Unilateral labyrinthectomy model |
Surgical destruction of the unilateral vestibular organ in rats and guinea pigs. |
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Schizophrenia-induced osteoporosis model |
Long-term administration of antipsychotic agents (such as haloperidol) in combination with ovariectomy or glucocorticoid induction |
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Cranial bone dissolution model |
Cranial implantation of titanium particles or inflammatory factors (TNF-α/polyethylene particles) |
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Global cerebral ischemic epilepsy model |
Seizures following bilateral common carotid artery ligation combined with hypotension-induced ischemia |
Disease Name
Disease model
Details
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Disease Name |
Disease model |
Construction method |
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Acute tubular necrosis |
Renal ischemia-reperfusion model |
Clamp both renal pedicles, release the vascular clamps to restore blood flow and reperfusion. |
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Bladder Obstructive Disease |
Bladder outlet obstruction model |
Surgical ligation of the urethra |
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Bacterial pyelonephritis |
Acute pyelonephritis model |
Temporary ligation of the ureter plus intravesical instillation of Escherichia coli |
Aniphe BioLab Inc.
Address:
Runcheng, No. 8 Longtai Road, Jiangbei New Area, Nanjing City, Jiangsu Province
Building 8, Science Park
Postal Code: 210007
Phone:025-8520 8061
Email:info@aniphebio.com(Consultation)
Email:order@aniphebio.com(Order)
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