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Skin-related disease models
Aniphe BioLab’s animal models for skin-related diseases are developed based on core pathological mechanisms, including the disruption of skin barrier function, immune-inflammatory responses, and imbalances in tissue repair. These models are primarily utilized for research into conditions such as atopic dermatitis, psoriasis, wound healing, and scar formation. By simulating processes like epidermal barrier damage, infiltration of inflammatory cells, and the aberrant release of cytokines, these models accurately replicate the onset and progression of skin diseases, providing a stable and reliable in vivo experimental foundation for mechanistic studies and pharmacological efficacy evaluation. In practical application, they are widely used to assess the efficacy of anti-inflammatory drugs, topical formulations, and skin-repair materials, as well as to investigate the mechanisms underlying skin immune regulation and regenerative repair.
Precision Modeling
System Verification
Repeatability
Accelerate R&D
Related Resources
Characteristics of Skin-Related Disease Models from Aniphe BioLab
In response to research needs in skin inflammation and barrier repair, Aniphe BioLab has established a standardized animal model system for skin‑related diseases, characterized by the following key features:
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It encompasses common models of atopic dermatitis, psoriasis, contact dermatitis, as well as wound healing and scar formation, thereby meeting the needs of inflammation and repair research. |
Standardized and controlled protocols were implemented for the induction method, stimulus intensity, and modeling duration to minimize the impact of variability in experimental procedures. |
By integrating skin lesion scoring, histopathology, barrier function testing, and inflammatory cytokine analysis, a comprehensive assessment of the inflammatory and reparative processes can be achieved. |
Provide raw experimental data, pathological images, and analytical results to ensure data traceability and compliance with publication and regulatory submission requirements. |
Animal models of skin-related diseases, by mimicking the processes of skin barrier disruption and inflammatory responses, provide a stable, standardized in vivo experimental platform for investigating the pathogenic mechanisms of skin disorders and for developing drugs and topical formulations.
Product List:
Disease Name
Disease model
Details
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Disease Name |
Disease model |
Construction method |
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Contact dermatitis/atopic dermatitis |
Dermatitis model |
Sensitization by a solution of 2,4-dinitrofluorobenzene acetone |
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Prolapsed hemorrhoids |
External hemorrhoid model |
Submucosal injection of carrageenan into the rectum induces swelling. |
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Vitiligo |
Vitiligo model |
Decolorization induction by monobenzone hydroquinone |
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Sjögren's syndrome |
Dryness syndrome model |
NOD.B10-H2 mice (spontaneous sialadenitis); submandibular gland adenoviral transduction of the BAFF gene |
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IgA vasculitis |
Allergic purpura model |
Intravenous injection of dextran plus lipopolysaccharide |
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Immune thrombocytopenia |
Idiopathic thrombocytopenic purpura model |
Intraperitoneal injection of antiplatelet serum |
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Pressure ulcer (full-thickness necrosis) |
Stage III pressure ulcer model |
Magnetic Compression Method |
Aniphe BioLab Inc.
Address:
Runcheng, No. 8 Longtai Road, Jiangbei New Area, Nanjing City, Jiangsu Province
Building 8, Science Park
Postal Code: 210007
Phone:025-8520 8061
Email:info@aniphebio.com(Consultation)
Email:order@aniphebio.com(Order)
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