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Cardiovascular disease model
Aniphe BioLab develops cardiovascular disease models based on key pathological mechanisms, including vascular remodeling, hemodynamic abnormalities, myocardial injury, and dysregulated inflammatory and immune responses. These models support in vivo research on atherosclerosis, pulmonary arterial hypertension (PAH), myocardial ischemia, and cardiomyopathies.
By reproducing vascular endothelial injury, lipid deposition, abnormal vascular smooth muscle cell proliferation, and myocardial ischemia-reperfusion injury, our models provide reliable platforms for disease mechanism studies and drug evaluation. Applications include lipid-lowering agents, antiplatelet drugs, vascular protective agents, and cardioprotective strategies, as well as research on vascular remodeling and myocardial repair.
Precision Modeling
System Verification
Repeatability
Accelerate R&D
Related Resources
Characteristics of the Aniphe BioLab Disease Model for Circulatory System Disorders
In response to the research needs surrounding vascular homeostasis imbalance and the mechanisms of cardiovascular injury repair, Ailinfei Biotechnology has established a standardized animal model system for circulatory system diseases, characterized by the following key features:
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Standardize the management of modeling protocols—including diet‑induced, surgical, and pharmacological/chemical injury–induced models—through unified SOPs to minimize inter‑batch experimental variability. |
By integrating hemodynamic monitoring, histopathological analysis, inflammatory cytokine assays, and cardiac functional assessments, a comprehensive evaluation of both structural and functional status can be achieved. |
Supports the staged research requirements of acute ischemic injury models and chronic vascular remodeling/heart failure models. |
We provide raw experimental data, imaging results (ultrasound/pathological sections), and comprehensive analytical reports, ensuring data traceability and compliance with publication and regulatory submission requirements. |
Animal models of circulatory system diseases, by mimicking vascular injury and myocardial dysfunction, provide a stable and reproducible in vivo experimental platform for investigating the mechanisms of cardiovascular disorders and evaluating therapeutic agents and intervention strategies.
Product List:
Disease Name
Disease model
Details
Myocardial ischemia MI/myocardial ischemia-reperfusion animal model
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Disease Name |
Disease model |
Construction method |
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Ventricular/Supraventricular Arrhythmia |
Arrhythmia model |
ISO, doxorubicin, epinephrine-induced |
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Atrial fibrillation |
Atrial fibrillation model |
Isoproterenol |
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Carotid artery thrombosis |
Deep Vein Thrombosis Model |
Ligation of inferior vena cava branches or repair of stenosis by suturing |
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Femoral artery thrombosis model |
FeCl/Rose Red + light-induced, electrically stimulated induction |
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Systemic sclerosis |
Systemic sclerosis model |
Bleomycin-induced |
Aniphe BioLab Inc.
Address:
Runcheng, No. 8 Longtai Road, Jiangbei New Area, Nanjing City, Jiangsu Province
Building 8, Science Park
Postal Code: 210007
Phone:025-8520 8061
Email:info@aniphebio.com(Consultation)
Email:order@aniphebio.com(Order)
WeChat Official Account
Video Account
Su Public Security Bureau Internet Information Service Filing No. 32010402001421