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Endocrine and Immune system models
Aniphe BioLab develops endocrine disease models based on key pathological mechanisms, including hormonal imbalance and metabolic dysregulation. These models support research on diabetes, obesity, thyroid disorders, and metabolic syndrome.
By reproducing insulin resistance, glucose and lipid metabolism disorders, and endocrine axis dysfunction, our models provide reliable in vivo platforms for disease mechanism studies and drug screening. Applications include glucose-lowering and metabolic therapies, endocrine target research, and studies of obesity, diabetic complications, and metabolic inflammation.
Precision Modeling
System Verification
Repeatability
Accelerate R&D
Related Resources
Characteristics of the Aniphe BioLab Endocrine System Disease Model
In response to research needs related to metabolic homeostasis disruption and hormonal dysregulation, Aniphe BioLab has established a standardized animal model platform for endocrine system disorders, ensuring model stability and data consistency.
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It encompasses common models of diabetes, obesity, thyroid dysfunction, and metabolic syndrome, meeting the needs of metabolic and endocrine research. |
Dietary induction, pharmacological modeling, and experimental timelines were uniformly controlled to minimize the impact of environmental and procedural variability on metabolic phenotypes. |
By integrating glycemic and lipid profiles, insulin sensitivity, and histopathological analyses, a comprehensive assessment of metabolic function and organ damage can be achieved. |
Provide raw experimental data, metabolic markers, and imaging results to ensure data traceability and compliance with publication and regulatory submission requirements. |
Animal models of endocrine system disorders, by mimicking the dysregulation of metabolic and hormonal homeostasis, provide a stable and reproducible in vivo experimental platform for investigating the pathogenesis of metabolic diseases and for drug development.
Product List:
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Disease Name |
Disease model |
Details |
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U87-MG-luc orthotopic animal model |
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Alzheimer’s disease AD animal model |
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Allergic encephalomyelitis animal model of AE |
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Animal model of post-traumatic stress disorder (PTSD) |
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Animal model of traumatic brain injury |
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Epilepsy animal model |
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Animal model of spinal cord injury |
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Anxiety disorder animal model |
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Animal model of electrical stimulation for traumatic brain injury |
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Animal model of traumatic brain injury |
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Chronic Unpredictable Mild Stress (CUMS) animal model |
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Animal model of cerebral hemorrhage |
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Cerebral ischemia MCAO animal model |
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Sepsis-induced brain injury model |
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Parkinson’s disease (PD) animal model |
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Mild hepatic encephalopathy model |
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Hypoxic-ischemic encephalopathy (HIE) animal model |
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Trigeminal neuralgia animal model |
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Animal models of sleep disorders/insomnia |
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Vascular dementia animal model |
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Animal model of depression |
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Animal model of autoimmune encephalomyelitis |
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Sciatic nerve compression animal model |
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Disease Name |
Disease model |
Construction method |
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Migraine model |
Nitroglycerin injection, dural inflammation-induced stimulation (application of inflammatory substances) |
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Pituitaryectomy model |
Surgical removal of the pituitary gland (via the transsphenoidal or transcranial approach) |
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Experimental model of osteomyelitis |
Tibial drilling and injection of Staphylococcus aureus |
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Hypoxic preconditioning model |
Severe ischemia is induced following repeated short-term hypoxic exposures (in normobaric or hypobaric chambers). |
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Unilateral labyrinthectomy model |
Surgical destruction of the unilateral vestibular apparatus in rats and guinea pigs. |
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Schizophrenia-induced osteoporosis model |
Long-term administration of antipsychotic agents (such as haloperidol) in combination with ovariectomy or glucocorticoid induction |
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Cranial bone dissolution model |
Cranial implantation of titanium particles or inflammatory factors (TNF-α/polyethylene particles) |
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Global cerebral ischemic epilepsy model |
Seizures following bilateral common carotid artery ligation and hypotension-induced ischemia |
Disease Name
Disease model
Details
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Disease Name |
Disease model |
Construction method |
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Hashimoto's thyroiditis |
Autoimmune thyroiditis model |
Iodine excess |
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Diabetic foot ulcer |
Diabetic foot disease model |
STZ-induced diabetes with full-thickness skin excision of the plantar surface |
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Diabetic chronic wounds |
Diabetic wound model |
STZ-induced diabetes with a dorsal wound |
Aniphe BioLab Inc.
Address:
Runcheng, No. 8 Longtai Road, Jiangbei New Area, Nanjing City, Jiangsu Province
Building 8, Science Park
Postal Code: 210007
Phone:025-8520 8061
Email:info@aniphebio.com(Consultation)
Email:order@aniphebio.com(Order)
WeChat Official Account
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