Aniphe BioLab

All

All
Insight
Research Services
Preclinical CRO
Animal Resource Bank

CN

中文 English

Insight

Step into Aniphe BioLab and, through the latest news, industry insights, brand updates, and a series of events, gain an in-depth understanding of our cutting-edge technological solutions in animal model development, efficient IVF‑based propagation, and preclinical efficacy evaluation—unlocking pioneering research tools and industry‑wide insights in the biopharmaceutical field.

Latest News

Naming Genetically Engineered Mice (Part II): From Being Understandable to Being Written Correctly

Naming Genetically Engineered Mice (Part II): From Being Understandable to Being Written Correctly

How should a multi-disease composite mouse model be constructed? Let’s take a look at the CKM approach.

How should a multi-disease composite mouse model be constructed? Let’s take a look at the CKM approach.

2026 CKM Guidelines Released: Chronic Diseases Enter the Era of Integrated Cardiorenal-Metabolic Management—It’s Time to Rethink Animal Models

2026 CKM Guidelines Released: Chronic Diseases Enter the Era of Integrated Cardiorenal-Metabolic Management—It’s Time to Rethink Animal Models

The endocrinology department manages blood glucose, the nephrology department handles proteinuria, the cardiology department oversees blood pressure and atherosclerotic plaques, and the obesity clinic focuses on weight management. Over the past few decades, we have tended to compartmentalize each patient into discrete disease modules, with each specialty addressing only one segment. Yet in reality, disease progression does not conform to departmental boundaries. In this patient, obesity, insulin resistance, hypertension, renal impairment, and cardiovascular risk are, at their core, distinct links in a single pathological cascade—driving one another and amplifying each other.

Technical Column

View all technical columns

Conducting efficacy evaluations for pulmonary arterial hypertension (PAH): how should one choose among the three classic animal models?

Image Name

2026/10/29

Conducting efficacy evaluations for pulmonary arterial hypertension (PAH): how should one choose among the three classic animal models?

Standardized Modeling Platform for Endometriosis: Recreating Inflammatory Pathology to Accelerate the Validation of New Gynecological Therapeutics

Image Name

2026/07/08

Don’t Rush to Replace Your ELISA Kit: Poor Experimental Results May Simply Reflect an Incorrect Time Point (Part 1)

Image Name

2026/07/15

From Oxidative Stress to Autophagy: Why Do These Classic Markers So Often Fail to Yield Reliable Results? (Part II)

Image Name

2026/07/17

huPBMC humanized immunocompetent mouse modeling platform: simulates human immune responses and enables evaluation of the efficacy of immunotherapeutics.

Image Name

2026/07/31

Service Cases

View all service cases

Customer Article | Nature Communications (IF = 12.121): Senescent-like macrophages mediate endplate‑induced vascularization in male mice via IL‑10 secretion

Customer Article | Nature Communications (IF = 12.121): Senescent-like macrophages mediate endplate‑induced vascularization in male mice via IL‑10 secretion

The cartilaginous endplate is located between the nucleus pulposus and the vertebral body; due to exposure to high shear stresses, it is prone to degeneration and injury. With aging or in the presence of other degenerative conditions, the cartilaginous endplate progressively undergoes sclerosis. Magnetic resonance imaging (MRI) findings of bone marrow lesions within the endplate are referred to as “Modic changes (MC)” and are strongly predictive of low back pain.

Project Article: J. Med. Chem | Phenotypic Screening and RFD‑Based Synergistic Strategies: In‑Depth Analysis of Multi‑Target Drug Design and Its Application in Alzheimer’s Disease Therapy

Project Article: J. Med. Chem | Phenotypic Screening and RFD‑Based Synergistic Strategies: In‑Depth Analysis of Multi‑Target Drug Design and Its Application in Alzheimer’s Disease Therapy

Alzheimer’s disease (AD) is a complex neurodegenerative disorder involving multiple pathogenic mechanisms, such as β‑amyloid accumulation and abnormal tau protein phosphorylation. Conventional drugs typically target a single molecular pathway, resulting in limited efficacy, whereas multi‑target drugs (MTDLs) can simultaneously modulate several targets; however, designing such compounds is extremely challenging and often relies on serendipitous discoveries.

Project Article PNAS (IF = 9.1) | Nano‑Immunomodulation of the Aβ‑Activated Feedback Mechanism in Microglia for Alzheimer’s Disease Therapy

Project Article PNAS (IF = 9.1) | Nano‑Immunomodulation of the Aβ‑Activated Feedback Mechanism in Microglia for Alzheimer’s Disease Therapy

Alzheimer’s disease (AD) is a common neurodegenerative disorder characterized by an insidious onset, slow progression, and the presence of behavioral and cognitive impairments, making it one of the most challenging conditions to treat worldwide. Amyloid‑β plaque deposition and neuroinflammation are key pathological hallmarks of AD; however, the molecular‑biological links between these two processes and the mechanisms by which they jointly drive the disease’s pathogenesis remain poorly understood.

Resource Center

View All Resource Centers

Balb/C mice

Jiangsu Aniphe BioLab, leveraging a high‑standard laboratory animal platform, offers a stable, long‑term supply of readily available BALB/c mice. As a classic inbred strain widely used in immunology research, tumor model development, and monoclonal antibody production, our mouse colonies boast a pure genetic background, consistent immune response profiles, and exceptional health. With ample in‑stock availability and a rapid response system, we can promptly meet your research and drug‑screening needs, ensuring high reproducibility and rigor in your experimental data.

B6-DIO-induced obese mice

B6-DIO-induced obese mice

A high-fat diet is used, and meticulous feeding begins at 6 weeks of age. Body weight is monitored daily, enabling personalized customization.

APP/PS1 double-transgenic mice (C57BL/6; C3H background)

APP/PS1 double-transgenic mice (C57BL/6; C3H background)

APP/PS1 double-transgenic mice are a commonly used mouse model for Alzheimer’s disease. They express a chimeric mouse/human amyloid precursor protein (Mo/HuAPP695swe) and a mutant human presenilin 1 (PS1-dE9).

Marketing Campaign

View All Marketing Campaigns

The International Congress on Aging Biology, CASC 2025, has concluded successfully! Aniphe BioLab looks forward to reuniting with you!

The International Congress on Aging Biology, CASC 2025, has concluded successfully! Aniphe BioLab looks forward to reuniting with you!

From April 18 to 20, the “2025 China Congress on Aging Science and the International Conference on Aging Biology,” co-organized by nine institutions including the Aging Cell Biology Branch of the Chinese Society for Cell Biology and hosted by entities such as the Oujiang Laboratory, was successfully held!

Exhibition Recap | The 15th Jinsha Geriatric Medicine Conference Concludes Successfully! Aniphe BioLab Looks Forward to Reuniting with You!

Exhibition Recap | The 15th Jinsha Geriatric Medicine Conference Concludes Successfully! Aniphe BioLab Looks Forward to Reuniting with You!

From June 26 to 28, the “2025 Academic Annual Conference of the National Clinical Research Center for Geriatric Diseases, the 15th Jinsha Geriatric Medicine Conference, and the 2025 Academic Conference of the Expert Committee on Smart Healthcare and Elderly Care of the Chinese Society of Gerontology and Geriatrics” was successfully held!

Unceasing Progress, Embarking on a New Journey | The 5th China Environmental and Health Conference of Aniphe BioLab Concludes Successfully!

Unceasing Progress, Embarking on a New Journey | The 5th China Environmental and Health Conference of Aniphe BioLab Concludes Successfully!

The three-day Fifth Conference on Environment and Health has concluded successfully. More than 1,300 participants from over 300 organizations—including medical and health institutions, research institutes, higher education institutions, as well as relevant enterprises, public institutions, and social organizations—attended the event.

Aniphe BioLab Inc.

Address:

Runcheng, No. 8 Longtai Road, Jiangbei New Area, Nanjing City, Jiangsu Province

Building 8, Science Park

Postal Code: 210007

Phone:025-8520 8061

Email:info@aniphebio.com(Consultation)

Email:order@aniphebio.com(Order)

Image Name

Image Name

Image Name

Image Name

Xiaohongshu

Bilibili

Image Name

WeChat Official Account

Image Name

Video Account

Website Development: China Enterprise Dynamics Nanjing|SEO

Business license

Su Public Security Bureau Internet Information Service Filing No. 32010402001421