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Custody, breeding, and purification

Aniphe BioLabtechnology has established an integrated laboratory animal resource platform that encompasses “genetic resource preservation—IVF‑mediated rapid expansion—SPF‑level purification—outsourced breeding and reproduction management,” offering end‑to‑end solutions spanning the entire lifecycle, from long‑term genetic resource storage to efficient, large‑scale population expansion. The platform ensures the secure storage and recovery of genetic resources through a cryopreservation system for sperm and embryos, leverages IVF‑ET technology to significantly shorten reproductive cycles, enhance batch consistency, and improve experimental reproducibility, and restores the research value of contaminated strains via SPF‑purification protocols. Additionally, it integrates a standardized outsourced breeding and reproduction system to enable full‑process traceability. This platform effectively reduces animal facility operating costs, enhances the efficiency and stability of model supply, and provides high‑quality, sustainable laboratory animal resources to support university research and biopharmaceutical R&D, thereby substantially boosting research productivity and translational capabilities.

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Custodial breeding and purification

Genetic Material Conservation and Revival

By cryopreserving sperm or fertilized eggs, we can effectively reduce the space required in SPF facilities and lower costs, while ensuring that valuable laboratory mouse strains remain unaffected by external environmental factors and diseases. By freezing mouse genetic material in liquid nitrogen, long-term stable preservation is achieved. Aniphe BioLab Laboratory has established a mature and comprehensive strain‑preservation protocol, serving major universities and research institutions. Sperm cryopreservation requirement: three 3–6‑month‑old male mice. Embryo cryopreservation requirement: two male mice (12–18 weeks old) and 30–40 female mice (4–8 weeks old). Cryopreservation duration: Each cryopreservation session provides free storage for 24 months, with automatic renewal upon expiration. Embryo cryopreservation is recommended for multi‑gene hybrid models or strains with specialized genetic backgrounds. For rat models, cryopreservation is currently possible only via embryo freezing.

Rapid propagation (IVF)

The in vitro fertilization (IVF) method was employed to ensure uniformity in the mice’s birth ages and to shorten the reproductive cycle, thereby enhancing the reliability of the experimental data.

Laboratory mouse purification

By leveraging the placenta’s barrier function, pathogenic agents from animal infections are eliminated, restoring the animals to SPF status.

Experimental mouse breeding and husbandry services

Aniphe BioLab can provide you with surrogate housing and breeding services for laboratory mice. Our SPF‑grade clean animal facility ensures full traceability and monitoring of the breeding process, allowing you to check the mice’s condition at any time. We also offer customized mouse breeding protocols and one‑stop genetic identification services.