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Focusing on cutting-edge technologies and research advancements, sharing Aniphe BioLab’s achievements in scientific innovation, Professional insights and practical experience in the fields of laboratory animals and preclinical research.
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2026-10-29
Naming Genetically Engineered Mice (Part II): From Being Understandable to Being Written Correctly
How should a multi-disease composite mouse model be constructed? Let’s take a look at the CKM approach.
2026-08-12
2026 CKM Guidelines Released: Chronic Diseases Enter the Era of Integrated Cardiorenal-Metabolic Management—It’s Time to Rethink Animal Models
A Guide to Safe Mouse Handling | Manual on Mouse Transport Protocols and Troubleshooting
2026/04/27
Uniting Efforts in Aging Science, Empowering Cutting-Edge Breakthroughs | Aniphe BioLab’s 2026 China Conference on Aging Science Concludes Successfully
From April 24 to 26, 2026, the China Congress on Aging concluded successfully. With the theme “Systemic Integration and Cross-Disciplinary Empowerment,” the conference brought together leading experts and scholars from both China and abroad in the field of aging research, focusing on cutting-edge topics such as the mechanistic elucidation of aging and related diseases, scientific measurement, and precision interventions, thereby jointly exploring a new future for life sciences.
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2026/03/06
[In Stock Flash Sale] Don’t let a shortage of mice slow you down! Special offer on 5XFAD and APP/PS1 transgenic mice—ideal for older‑age studies!
Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by cognitive impairment. Its core pathological hallmarks include β‑amyloid (Aβ) deposition, neurofibrillary tangle formation, and neuroinflammation, and it is rapidly emerging as one of the leading causes of disability and mortality among the elderly.
2026/02/28
Practical Knowledge Sharing: Does lung tissue collected after bronchoalveolar lavage (BALF) affect the pathological architecture?
The lavage procedure essentially involves the physical flushing of the alveolar space, and as such may exert additional effects on the structural integrity of lung tissue. These effects are primarily manifested in the following aspects:
2026/02/12
New Discovery in Nature: A signaling pathway reverses T-cell exhaustion, enabling a “precision breakthrough” in cancer immunotherapy!
T-cell exhaustion is a dysfunctional state that arises under the prolonged influence of chronic infection or the tumor microenvironment, characterized by the loss of effector functions and the sustained high expression of inhibitory receptors such as PD‑1 and TIM‑3. Based on functional heterogeneity, exhausted T cells can be classified into progenitor‑like exhausted T cells (Tₚᵣₒ₉) and terminally exhausted T cells (Tₜₑₓ); among these, Tₜₑₓ cells exhibit virtually no response to immunotherapy and represent the primary cause of treatment failure in clinical settings.
T cell exhaustion is a dysfunctional state that arises under the prolonged influence of chronic infection or the tumor microenvironment, characterized by the loss of effector functions and the sustained high expression of inhibitory receptors (such as PD‑1 and TIM‑3). Based on functional heterogeneity, exhausted T cells can be classified into progenitor‑like exhausted T cells (Tₚᵣₒ₉) and terminally exhausted T cells (Tₜₑₓ); among these, Tₜₑₓ cells exhibit virtually no response to immunotherapy and represent the primary cause of treatment failure in clinical settings.
2026/01/29
New Policy Explained: What Changes Have Been Made to the 2026 National Natural Science Foundation of China Application and Completion Policies?
Recently, in accordance with the arrangements for the administration of funding under the National Natural Science Foundation of China (hereinafter referred to as the “Science Fund”), a notice has been issued regarding matters related to the application and final reporting of National Natural Science Foundation projects for the year 2026.
2026/01/21
J. Med. Chem.| A comprehensive, innovative strategy for anti‑gastric cancer based on dual targeting and immune activation, employing iridium(III) complexes
Gastric cancer, a globally prevalent malignancy, exhibits incidence and mortality rates comparable to those of lung cancer, making it one of the leading causes of significant global health burden. Because most patients are diagnosed at an advanced stage, their prognosis remains extremely poor. Moreover, compared with other cancers of similar incidence and mortality, our understanding of the molecular mechanisms underlying gastric carcinogenesis and progression remains markedly incomplete, a gap that severely hinders the development of innovative therapeutic strategies and breakthroughs.
2025/12/18
[Good News] Aniphe BioLab has won the provincial first prize in the “Right Here in Jiangsu” Youth Entrepreneurship Competition!