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Focusing on cutting-edge technologies and research advancements,
sharing Aniphe BioLab’s achievements in scientific innovation, Professional insights
and practical experience in the fields of laboratory animals and preclinical research.

Disease Model | Chronic Atrophic Gastritis (CAG) and Gastric Cancer (GC) in the Upper Gastrointestinal Tract
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2023/08/18

Disease Model | Chronic Atrophic Gastritis (CAG) and Gastric Cancer (GC) in the Upper Gastrointestinal Tract

Chronic atrophic gastritis (CAG) is a common, frequently occurring, and refractory chronic gastric disease characterized by localized or widespread atrophy of the intrinsic glands in the gastric mucosa, with a reduction in their number; thinning of the gastric mucosa; thickening of the lamina propria; and, in some cases, metaplasia of pyloric glands and intestinal metaplasia, as well as the presence of dysplasia.

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Join us in observing World Hepatitis Day—learn about your liver and take care of your health!
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2023/08/02

Join us in observing World Hepatitis Day—learn about your liver and take care of your health!

July 28, 2023, marked the 13th World Hepatitis Day. This year, China’s campaign theme is “Uphold Early Prevention, Strengthen Testing and Detection, and Standardize Antiviral Treatment,” aiming to further raise public awareness of hepatitis prevention and control, mobilize the entire society to take proactive action, promote the implementation of comprehensive measures such as early prevention, early testing, and early treatment, improve public health, and strive to eliminate the harm caused by hepatitis.

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Disease Models | A Comprehensive Guide to the Various Methods for Establishing Pulmonary Hypertension (PH) Models!
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2023/07/24

Disease Models | A Comprehensive Guide to the Various Methods for Establishing Pulmonary Hypertension (PH) Models!

Pulmonary hypertension (PH) is a refractory pulmonary vascular disease characterized by pulmonary vascular remodeling and elevated pulmonary arterial pressure. It represents a hemodynamic and pathophysiological state in which pulmonary arterial pressure rises above a defined threshold, owing to known or unknown etiologies, and may ultimately lead to right ventricular hypertrophy, heart failure, and death.

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Has the goddess fallen, and is depression difficult to treat? Common modeling approaches for animal depression models ↓
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2023/07/17

Has the goddess fallen, and is depression difficult to treat? Common modeling approaches for animal depression models ↓

In recent years, the incidence of depression has been steadily increasing, posing a serious threat to both physical and mental health. Treatment for depression primarily relies on antidepressant medications; however, currently available antidepressants have certain limitations. A relatively mature, stable, and convenient animal model of depression is crucial for investigating its pathogenic mechanisms and for the development of new antidepressant therapies.

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Disease Models | Hepatic Fibrosis (HF) and Hepatocellular Carcinoma (HCC) (Part II)
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2023/07/10

Disease Models | Hepatic Fibrosis (HF) and Hepatocellular Carcinoma (HCC) (Part II)

The development of hepatocellular carcinoma is a multistep pathological process, characterized by a gradual progression from chronic liver injury through hepatitis, hepatic fibrosis, and cirrhosis, ultimately culminating in hepatocellular carcinoma. This article continues to explore “Disease Models: Hepatic Fibrosis (HF) and Hepatocellular Carcinoma (HCC) – Part II,” providing insights into the relevant knowledge surrounding hepatocellular carcinoma models. Let’s take a closer look.

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Disease Models | Hepatic Fibrosis (HF) and Hepatocellular Carcinoma (HCC) (Part I)
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2023/07/03

Disease Models | Hepatic Fibrosis (HF) and Hepatocellular Carcinoma (HCC) (Part I)

Chronic liver disease, over a prolonged period, leads to hepatic fibrosis through inflammatory injury of hepatocytes. If left untreated, the excessive deposition of extracellular matrix within the liver progresses to cirrhosis and may ultimately culminate in hepatocellular carcinoma. Consequently, research on animal models of hepatic fibrosis and hepatocarcinogenesis is of great significance for the prevention and treatment of liver diseases.

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Disease Models | Methods for Establishing Liver Resection and Hepatic Ischemia Models!
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2023/06/20

Disease Models | Methods for Establishing Liver Resection and Hepatic Ischemia Models!

Partial hepatectomy–induced liver regeneration and hepatic ischemia-reperfusion models are commonly used to study acute liver injury, liver tumors, and liver regeneration.

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Disease Models | A Comprehensive Guide to the Mouse Orthotopic Liver Tumor Model
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2023/06/20

Disease Models | A Comprehensive Guide to the Mouse Orthotopic Liver Tumor Model

Establishing tumor animal models is an essential approach for investigating the mechanisms of tumorigenesis and conducting research on cancer therapies. These models can replicate the natural biological processes of human tumors, including tumorigenesis, progression, invasion, and metastasis. A well‑constructed hepatocellular carcinoma animal model serves as an excellent alternative for studying the development of human liver cancer and the host’s anti‑tumor immune responses.

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