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The various in vitro drug‑screening models established can provide an effective evaluation of drug efficacy and serve as a robust approach for early‑stage drug discovery.

The various in vitro drug‑screening models established can provide an effective evaluation of drug efficacy and serve as a robust approach for early‑stage drug discovery.

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Drug screening
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Drug screening

The various in vitro drug‑screening models established can provide an effective means of evaluating drug efficacy and serve as a robust approach for early‑stage drug discovery.


I. Service Overview
Screening candidate drugs can increase the success rate of new‑drug development, reduce R&D costs, and shorten the time required to bring a new drug to market.
Cellular‑level drug screening is a simple and practical approach for assessing drug functions at the cellular level. It features low experimental costs, short assay durations, and excellent reproducibility, making it an effective method for early‑stage drug discovery.


II. Technical Principles and Advantages
Technical Principle: Under appropriate culture conditions, cells can grow and proliferate in vitro, exhibiting functions and characteristics closely associated with disease. Our cell bank houses hundreds of cell lines, and we possess extensive hands-on experience in the isolation and culture of primary cells. Based on this expertise, we have established a variety of in vitro drug‑screening models that provide robust assessments of drug efficacy, serving as an effective approach for early‑stage drug discovery.
Advantages: Compared with biochemical assays, this technique better reflects the drug’s physiological‑level functions. Compared with animal studies, it is easier to perform, has a shorter experimental timeline, and exhibits excellent reproducibility.


III. Operating Procedure
◆ Cell culture and seeding;
◆ Drug treatment; (Traditional Chinese medicine compound formulas can also be used to prepare drug-containing serum)
◆ Cell physiological function assays and drug target identification; (including cell cycle analysis, cell proliferation and apoptosis assays, flow cytometry, co-immunoprecipitation, ELISA, reporter gene systems, and various other molecular biology and protein‑immunology techniques)
◆ Data statistical analysis;
◆ Writing and submitting laboratory reports.


IV. Experimental Service Period
The specific cycle will be determined after evaluation.


V. Data Provision
Provides cell images, authentic assay data, and analytical results.