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2026-10-29

Naming Genetically Engineered Mice (Part II): From Being Understandable to Being Written Correctly

2026-10-29

How should a multi-disease composite mouse model be constructed? Let’s take a look at the CKM approach.

2026-08-12

2026 CKM Guidelines Released: Chronic Diseases Enter the Era of Integrated Cardiorenal-Metabolic Management—It’s Time to Rethink Animal Models

2026-08-12

A Guide to Safe Mouse Handling | Manual on Mouse Transport Protocols and Troubleshooting

This website helps you understand transgenic mice in scientific literature!

　　For researchers new to transgenic mice, without a systematic overview, it can be challenging to decipher the meaning of various model designations—and when reading the literature, the myriad names of transgenic mouse strains can seem downright confusing. Questions such as how these mice are generated, what phenotypes they exhibit, which research areas they are suited for, and how to use them can be particularly daunting. Today, I’d like to recommend a website dedicated to mouse models. Each strain on this site is accompanied by a detailed description, allowing you to learn in conjunction with the literature you’re reviewing, thus making the concepts much easier to grasp. Below, we’ll take the Nlrp3 knockout mouse model as an example to walk you through its features.

　　After opening the website, enter the gene name “Nlrp3” in the search box; relevant mouse information will automatically appear. For the KO mice we’re looking for, there’s a hyphen (“–”) next to them—select the entry you wish to query. As for other entries listing mice with point mutations, interested users can click through to learn more.

　　After clicking, the website provides a brief introduction to the mouse strain, allowing us to gain a general understanding of this mouse model.

　　Click on the mouse strain name to access the detailed information page for that strain:

　　Then click “READ MORE.” On this page, you can find a detailed description of the mouse, including the location and size of the targeted gene knockout, whether homozygous mice are fertile, and the phenotypes that have been identified. You can also access information on the mouse’s construction process and relevant references.

　　Clicking on “Genetics” will display a detailed gene description:

　　In the Technical Support section, you can also find information on genetic identification methods, husbandry practices, breeding protocols, and literature‑based import requirements. Simply click on the blue‑text links to view the details.

　　If everyone can make frequent use of this website, I’m sure you’ll never again struggle to understand transgenic mice in scientific literature!

　　Website link: https://www.jax.org/mouse-search

　　Finally, Aniphe BioLab can provide agency import services for mice from resource repositories such as Riken and Jax. If you have identified the mouse strain you need, please contact us—we’ll be happy to arrange its import.

Treat Laboratory Animals with Care, Honor Animal Heroes—A Themed Commemorative Event for Animal Experimentation Week by Aniphe BioLab

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