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Standards and Requirements for Microbiology Laboratory Design

　　Microbiology laboratories are primarily used for research in microbiology, biomedicine, biochemistry, animal experimentation, genetic engineering, and the production of biological products. The following sections will introduce the design codes, standards, and requirements for microbiology laboratories.

　　I. Standards for the Design and Planning of Microbiology Laboratories

　　Each space in the microbiology laboratory must be independently configured, with the layout designed according to the specific tasks performed. A centralized changing room is provided at the entrance, and the culture rooms can be arranged as multiple individual spaces—such as mold‑culture rooms, bacterial‑culture rooms, solid‑medium culture rooms, and liquid‑medium culture rooms—depending on the cultivation conditions and microbial types.

　　1. Clean Laboratory: The clean laboratory is located in a corner along the perimeter of the facility, with access controlled by a sealed door. Rooms requiring strict cleanliness are positioned in areas less subject to personnel interference, while ancillary spaces are situated on the exterior. The layout takes into account the workflow of microbiological experiments, ensuring efficient segregation of personnel and material flows. To manage personnel access (human traffic), only one sealed door provides entry into the main clean zone of the microbiology laboratory. Personnel enter via the corridor into a preparation room, then proceed through a first changing area, a second changing area, and a buffer zone before entering the operational area. Material transfer is facilitated by a pass-through window. Exhaust outlets are equipped with high-efficiency filters, and supply air outlets incorporate high-efficiency filter‑equipped static pressure boxes. Airflow within the room follows an upward supply and downward exhaust configuration, with exhaust vents arranged on one side and free of obstructions. A differential pressure valve automatically regulates indoor pressure, maintaining a positive-pressure clean environment.

　　2. Washing Room: The dimensions of the washing room are determined by the daily workload and should generally be no smaller than a single‑occupancy room. The room should be located near the culture room, with comprehensive water supply and drainage facilities. The washbench must be resistant to heat and acids, and the room should be equipped with utensil cabinets, drip racks, drying racks, side tables, and other necessary fixtures. The floor should have an adequate drainage slope and a floor drain.

　　3. Preparation Room: The room shall be equipped with a laboratory bench and reagent cabinets, both of which must be electrically insulated and heat‑resistant; the bench itself must be water‑proof and corrosion‑resistant. It should also include plumbing for hot and cold water supply. For operations involving powders and sieving, appropriate equipment must be provided. Local exhaust ventilation is required, with an exhaust hood installed.

　　4. Culture Room: Primarily equipped with various incubators and shakers, it requires a relatively stable temperature and an adequate power supply.

　　II. Design and Planning Requirements for Microbiology Laboratories

　　1. When designing a microbiology laboratory, it is essential to rationally plan the layout of its various functional areas, typically including a preparation room, a microbial culture room, an instrument sterilization and cleaning room, a purified water room, a testing room, a strain preservation room, and a storage room.

　　2. Each department shall be a separate, independent area and be equipped with an isolation door. In particularly critical laboratories, a buffer zone must be established, allowing personnel entering the laboratory to undergo secondary decontamination and change their attire in this zone.

　　3. The interior surfaces of the laboratory’s enclosure (including the buffer room) must be smooth, corrosion‑resistant, and waterproof to facilitate disinfection and cleaning. All joints and gaps must be reliably sealed. All doors within the laboratory shall be self‑closing.

　　4. Except for the observation window, no other windows shall be installed. The observation window must have a sealed structure, and the glass used must be shatterproof. The floor shall be leak‑proof, smooth yet non‑slippery. Floor tiles and terrazzo flooring with joints are prohibited.

　　5. The ventilation and air-conditioning system shall be a direct-exhaust system; a partial-recirculation system is prohibited.

　　6. Laboratory furniture must be sturdy and reliable. To facilitate cleaning, adequate clearance should be maintained between all types of furniture and equipment. Dedicated benches (or racks) for housing biological waste containers shall be provided. The edges, corners, and protruding parts of furniture and equipment should be smooth and free of burrs; rounded profiles are recommended.

　　The foregoing provides an overview of the relevant design codes, standards, and requirements for microbiology laboratories, for your reference.

　　》》 Microbial laboratory design and planning, as well as laboratory renovation and construction, are required. Please call Guangzhou Zhuoping Laboratory.

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