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Gene editing and

Rapid propagation

An integrated solution spanning from precise gene editing to efficient large-scale propagation.

We offer a full‑service platform covering transgenic construct design, transgenic animal generation, and quality control, helping research institutions and biopharmaceutical companies significantly shorten model development timelines while enhancing experimental reproducibility and research efficiency.

Multiple editing strategies supported

CRISPR/Conditional Editing

Humanized Knock-in/Disease Model Customization

SPF Standard System

Specialized Propagation Platform

Ensuring the quality and stability of the slow mode

End-to-end one-stop service

From “genetic design” to “lock‑in‑type delivery”—efficient, hassle‑free, and more reliable.

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I. Gene Editing Technology Services

(Precision Genome Editing)

Leveraging a well-established CRISPR gene-editing platform, coupled with optimized embryo manipulation and rigorous molecular validation protocols, we deliver highly efficient and precise genetic engineering services.

● CRISPR/Cas9 gene knockout (KO)
● Gene knock-in (KI)
● Construction of a Point Mutation Model
● Conditional gene editing (Cre–loxP system)
● Polygenic Combined Editing Model

II. Rapid Propagation System

(Rapid Breeding System)

Establish a standardized, rapid propagation system based on SPF‑grade animal platforms, enabling efficient expansion from a single founder individual to a stable experimental colony.

Establishing a standardized, rapid‑propagation management system for the large-scale expansion of SPF‑grade animals based on an SPF‑level animal platform.

Embryo Transfer (ET) Technology Platform

In Vitro Fertilization (IVF)-Assisted Reproduction System

Construction and Revival of Cryopreserved Embryo/Sperm Banks

Control and Screening of Genetic Background Stability

III. Disease Model Construction and Custom Development

(Custom Disease Models)

Catering to both basic research and drug development, we offer customized animal models for a wide range of diseases, supporting end-to-end research needs from target validation to efficacy assessment.

● Neurodegenerative disease models (e.g., AD, PD)
● Tumor Initiation and Metastasis Models
● Metabolic disease models (diabetes, obesity, etc.)
● Immunity and inflammation-related models
● Cardiovascular disease model
● Generation of humanized mouse models

IV. Service Process (From Idea to Model)

We employ a standardized five-step service process to ensure efficient project execution:

Requirements Communication

Clearly define the research objectives, key information, and experimental design requirements.

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Technical Solution Design

Providing gene-editing strategies and
Model Construction and Limb Line Assessment

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Implementation of gene editing

Completion of construct assembly and embryo manipulation
With the first-generation Tixuan

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Rapid propagation and screening

Establish a stable well for the targeted group.
Conduct quality verification

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Support and Continuous Delivery

Delivery of the cabinet model + technical service report + subsequent expansion and support

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V. Technical Advantages (Why Choose Us)

Compared with traditional model-building approaches, we have achieved systematic improvements in the following areas:

Shorter cycle

Significantly shorten the time required for model construction and propagation.

Higher success rate

Optimizing gene editing and screening workflows

Higher consistency

Strict genetic background control system
 

Integrated platform

End-to-end coverage from design to delivery
 

End-to-end traceability

Complete Recording and Management of Experimental Data