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Focusing on cutting-edge technologies and research advancements,
sharing Aniphe BioLab’s achievements in scientific innovation, Professional insights
and practical experience in the fields of laboratory animals and preclinical research.

An efficient IVF‑ET assisted reproductive technology platform, enabling rapid colony expansion in just 45 days and fully meeting the needs of research laboratories for mice of all strains.
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2026/06/12

An efficient IVF‑ET assisted reproductive technology platform, enabling rapid colony expansion in just 45 days and fully meeting the needs of research laboratories for mice of all strains.

When faced with these challenges in natural breeding, IVF‑ET—In Vitro Fertilization–embryo Transfer—technology enables you to obtain genetically diverse, age‑synchronized mouse offspring quickly and effortlessly. With mouse reproduction accelerated by up to 50%, your paper will be one step ahead!

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J Exp Med (II): A Bulk CRISPR Screening Platform—Functional Dissection from T Cells to the Entire Immune System
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2026/06/11

J Exp Med (II): A Bulk CRISPR Screening Platform—Functional Dissection from T Cells to the Entire Immune System

This article focuses on the latest technological advances in bulk CRISPR screening, including novel editing tools, in vivo screening strategies, and expanded applications to immune cell types beyond T cells.

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[Guide to Avoiding Common Pitfalls] Always running into trouble with mouse genotyping? Read this guide and master mouse genotyping with ease!
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2026/06/11

[Guide to Avoiding Common Pitfalls] Always running into trouble with mouse genotyping? Read this guide and master mouse genotyping with ease!

Mouse tail genotyping is a widely used genetic experimental method for determining the genotype of laboratory mice. Genotype identification is indispensable in the application of genetically engineered mice.

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A crackdown on fraud is sweeping the research community; amid widespread irregularities, a robust quality‑assurance system has become the cornerstone of credibility.
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2026/06/05

A crackdown on fraud is sweeping the research community; amid widespread irregularities, a robust quality‑assurance system has become the cornerstone of credibility.

Recently, academic integrity‑monitoring bloggers have successively exposed instances of research misconduct among scholars at several prestigious universities, sending shockwaves through the entire scientific community. Persistent revelations of irregular data patterns and image manipulation have brought the crisis of trust in published research squarely into the spotlight. With data increasingly being overly embellished and risks of academic misconduct pervasive, how can principal investigators safeguard academic integrity and mitigate these risks?

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High-Efficiency COPD Standardized Modeling Platform: Shortens the preclinical trial cycle and enables rapid efficacy evaluation of novel respiratory therapeutics.
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2026/06/05

High-Efficiency COPD Standardized Modeling Platform: Shortens the preclinical trial cycle and enables rapid efficacy evaluation of novel respiratory therapeutics.

The use of animal models is an indispensable tool in COPD research, enhancing our understanding of the fundamental mechanisms underlying COPD’s physiology, pathophysiology, and treatment.

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J Exp Med: Why Do We Need “Causal Systems Immunology”? — The Historical Context of CRISPR Screening
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2026/06/03

J Exp Med: Why Do We Need “Causal Systems Immunology”? — The Historical Context of CRISPR Screening

The immune system is one of the most complex regulatory networks in living organisms. T cells, B cells, NK cells, dendritic cells, macrophages—dozens of cell types collaborate with exquisite precision across time and space to defend against pathogens, monitor tumors, and maintain homeostasis. However, for a long time, immunological research has been confronted with a fundamental dilemma:

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Key Insights | A Comprehensive Guide to Renal AAV Delivery: Five Local Injection Strategies to Overcome the Kidney Barrier and Achieve Efficient Transduction
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2026/06/03

Key Insights | A Comprehensive Guide to Renal AAV Delivery: Five Local Injection Strategies to Overcome the Kidney Barrier and Achieve Efficient Transduction

As the central organ of the urinary system, the kidney comprises a complex functional unit composed of more than 20 distinct cell types, including the renal corpuscle—comprising endothelial cells, podocytes, and mesangial cells—and the renal tubule, which is predominantly lined by epithelial cells. Its unique physiological barriers, such as the glomerular basement membrane with slit pores measuring only 10 nm in diameter, render systemic administration of adeno‑associated viruses (AAVs) poorly effective; approximately 90% of viral particles are sequestered by the liver, resulting in suboptimal renal targeting efficiency.

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From “Functional Screening” to “Causal Systems Immunology”: A Three-Year Journey Across Two Reviews by Shi and Chi
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2026/05/29

From “Functional Screening” to “Causal Systems Immunology”: A Three-Year Journey Across Two Reviews by Shi and Chi

From 2023 to 2026, this field underwent a significant self-upgrade.

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